The Maingau Clinic of the Red Cross (Klinik Maingau vom Roten Kreuz) is a historic general hospital in central Frankfurt am Main, Germany, operated by the Frankfurter Rotkreuz-Kliniken e.V. part of the German Red Cross health system. It has served the community for more than a century, offering high-quality medical and nursing care as a nonprofit institution rooted in the humanitarian tradition of the Red Cross. 

Located at Scheffelstraße 2–14 near Eschenheimer Anlage park, the clinic provides comprehensive medical services across multiple specialties, including orthopaedics and trauma surgery, urology, internal medicine, gynaecology, oncology and more. As a Belegarzt-klinik (hospital with attending physicians), patients often benefit from continuous care by the same specialist before, during and after hospital stays. 

Over the years, the clinic has become a well-established healthcare provider in the Rhein-Main region, known for combining professional expertise with compassionate care in a central urban setting.